Yintoni i-S-Adenosyl-L-methionine (SAM) Umgubo?
I-Powder S-adenosyl-L-methionine (edla ngokubizwa ngokuba yi "SAM-e" "SAM") yinxalenye yemichiza eyenzeka ngokwemvelo ekhoyo kuzo zonke iiseli zomzimba apho iyimfuneko kwiindlela ezingaphezu kwama-200 zemetabolism. Yinombolo yeCAS ngu-29908-03-0.
I-S-adenosyl-L-methionine (SAM) ibandakanyeka ekubunjweni, ekusebenzeni, nasekuqhekekeni kwezinye iikhemikhali emzimbeni, kubandakanywa amahomoni, iiprotheni kunye neziyobisi ezithile. Umzimba uyisebenzisela ukwenza iikhemikhali ezithile ezidlala indima kwintlungu, ukudakumba, isifo sesibindi kunye nezinye iimeko.
Abantu badla ngokuthatha i-SAMe ngenxa yokudakumba kunye ne-osteoarthritis. Ikwasetyenziselwa ukuxhalaba, isifo sesibindi, i-fibromyalgia, i-schizophrenia, kunye nezinye iimeko ezininzi, kodwa akukho bungqina besayensi obufanelekileyo bokuxhasa oku kusetyenziswa.
I-SAMe ibifumaneka njengesongezelelo sokutya e-US ukusukela ngo-1999, kodwa ibisetyenziswa njengechiza elimiselweyo e-Itali, eSpain, naseJamani amashumi eminyaka. Ifumaneka ngaphandle kwencwadi kagqirha eUnited States nakwamanye amazwe.
Yintoni i-S-Adenosyl-L-methionine Disulfate Tosylate Powder?
I-Powder S-Adenosyl-L-methionine Disulfate Tosylate yifom ye-Disulfate Tosylate ye-S-Adenosyl-L-methionine (SAM), inombolo yayo ye-CAS yi-97540-22-2, eyaziwa ngokuba yi-Ademetionine disulfate tosylate, S-Adenosylfateonini. tosylate, AdoMet disulfate tosylate.
Ngumgubo oMhlophe ukuya kumhlophe wehygroscopic, unyibilika ngokukhululekileyo emanzini, awunyibiliki kwi-hexane kunye ne-acetone. I-S-Adenosyl-L-methionine disulfate tosylate (i-Ademetionine disulfate tosylate) yeyona nto iphambili ye-methyl donor eyenziwe kuzo zonke iiseli ezanyisayo kodwa ininzi kakhulu esibindini. I-Ademetionine disulfate tosylate powder isetyenziswa kakhulu kwizongezo zokutya njengeyona nto iphambili.
Isebenza njani i-S-Adenosyl-L-methionine (SAM) kunye ne-S-Adenosyl-L-methionine Disulfate Tosylate?
Isebenza njani i-S-Adenosyl-L-methionine (SAM) kunye ne-Ademetionine disulfate tosylate emzimbeni? Yintoni indlela yokusebenza? I-S-Adenosyl-L-methionine (SAM) yikhompawundi eyenzeka ngokwemvelo efumaneka phantse kuzo zonke iithishu kunye nolwelo emzimbeni. Ibandakanyeka kwiinkqubo ezininzi ezibalulekileyo. I-SAMe idlala indima kwi-immune system, igcina iimbumba zeeseli, kwaye inceda ukuvelisa kunye nokuphula iikhemikhali zengqondo, ezifana ne-serotonin, i-melatonin, kunye ne-dopamine. Isebenza kunye ne-vitamin B12 kunye ne-folate (i-vitamin B9). Ukunqongophala kwe-vitamin B12 okanye i-folate kunokunciphisa amanqanaba e-SAMe emzimbeni wakho.
Izifundo ezininzi zibonisa ukuba i-SAMe inceda ukukhulula iintlungu ze-osteoarthritis. Olunye uphononongo lucebisa ukuba i-SAMe inokunceda ukunyanga ukudakumba. Abaphandi baye bahlola ukusetyenziswa kwe-SAMe kunyango lwe-fibromyalgia kunye nesifo sesibindi kunye neziphumo ezixubileyo. Uninzi lwezifundo zokuqala zasebenzisa i-SAMe enikwa nge-intravenously okanye njengenaliti. Kutshanje abaphandi baye bakwazi ukujonga iziphumo ze-SAMe ezithathwe ngomlomo.
Umzimba usebenzisa i-Ademetionine disulfate tosylate ukwenza iikhemikhali ezithile emzimbeni odlala indima kwintlungu, ukudakumba, isifo sesibindi kunye nezinye iimeko. Abantu abangenzi ngokwaneleyo i-Ademetionine disulfate tosylate ngokwendalo banokuncedwa ngokuthatha i-Ademetionine disulfate tosylate njengesongezelelo.
Ziziphi iiNzuzo ze-S-Adenosyl-L-methionine (SAM) kunye ne-S-Adenosyl-L-methionine Disulfate Tosylate powder?
I-S-adenosyl-L-methionine (SAM) yikhompawundi efumaneka ngokwemvelo emzimbeni. I-SAMe inceda ukuvelisa kunye nokulawula iihomoni kunye nokugcina iimbumba zeeseli. I-SAM ithandwa kakhulu kwihlabathi njengezongezo zokutya. Ziziphi iingenelo zokusetyenziswa kwe-S-Adenosyl-L-methionine (SAM)?
-I-Antidepressant
Uphononongo lwezonyango olwenziwe kwangoko ngo-1973 lubonise ukuba i-S-adenosyl-L-methionine (SAM) ineziphumo zokuthomalalisa uxinzelelo. Kwiminyaka eyi-2 ezayo, ukusebenza kwe-S-adenosyl-L-methionine (SAM) ekuphatheni izifo ezixinzelelekileyo kwaqinisekiswa kwi> Izilingo zeklinikhi ze-40. Amanqaku amaninzi okuphonononga ashwankathela ezi zifundo apapashwa kwi-1988, 1989, 1994, kunye ne-2000.
-Uncedo ngeOsteoarthritis
Izifundo ezininzi ezithelekisa ukusetyenziswa kwe-S-adenosyl-L-methionine (SAM) kunye neziyobisi ezichasene nokudumba zibonise ukuba nganye ibonelela ngesiqabu esifanayo kunye nokuphucula ukusebenza kwamalungu, kodwa i-S-adenosyl-L-methionine (SAM) ivelise iziphumo ebezingalindelekanga ezimbalwa. . Inani elincinane lophononongo alikabonisi iziphumo ezifanayo.
-Fibromyalgia
I-S-adenosyl-L-methionine (SAM) inokusebenza ekunciphiseni iimpawu ze-fibromyalgia, kuquka intlungu, ukukhathala, ukuqina kwasekuseni kunye nokudandatheka. Kodwa uninzi lwezifundo lusebenzise uhlobo olutofwayo lwe-S-adenosyl-L-methionine (SAM). Phakathi kwezifundo ezivavanye iidosi ze-S-adenosyl-L-methionine (SAM) ngomlomo, ezinye zifumanise ukuba ziyasebenza ekwehliseni ezi mpawu ngelixa ezinye zingafumani ncedo.
-Isifo sesibindi
Abantu abanesifo sesibindi bahlala bengakwazi ukwenza i-S-adenosyl-L-methionine (SAM) emizimbeni yabo. Izifundo zokuqala zibonisa ukuba ukuthatha i-S-adenosyl-L-methionine (SAM) kunokunceda ukunyanga isifo esingapheliyo sesibindi esibangelwa ngamayeza okanye utywala.
-Ukuphazamiseka kwengqondo
Ubungqina bokuqala bubonisa ukuba i-S-adenosyl-L-methionine (SAM) inokuphucula iimpawu zengqondo, ezifana nokukwazi ukukhumbula ulwazi kunye nokukhumbula amagama. Abaphandi bakrokrela ukuba i-S-adenosyl-L-methionine (SAM) isebenza kwimimandla yengqondo elawula ukubonakaliswa kofuzo lweeprotheni ze-amyloid, enye yeempawu zesifo se-Alzheimer.
Ithatha ixesha elingakanani ukuba i-S-Adenosyl-L-methionine (SAM) isebenze?
Uninzi lwangoku lwangoku lwe-antidepressants lunesiqalo sokulibaziseka kwesenzo, ngoko ke ukuphucuka okungaguqukiyo kwisimo kunokubonakala kuphela emva kweeveki ezine ukuya kwezintandathu zokusetyenziswa kwemihla ngemihla. Ngokwahlukileyo, i-S-Adenosyl-L-methionine (SAM) inokuqala ngokukhawuleza kwesenzo, ngokuqhelekileyo kwiveki enye yokuqalisa unyango.
Zeziphi iziphumo ezisecaleni zokuthatha umgubo we-S-Adenosyl-L-methionine (SAM)
I-S-adenosyl-L-methionine (SAM) ibonakala ikhuselekile kwaye inokusebenza ekunyangeni ukudakumba kunye ne-osteoarthritis. Nangona kunjalo, i-S-adenosyl-L-methionine (SAM) inokunxibelelana ne-antidepressants. Musa ukusebenzisa i-S-adenosyl-L-methionine (SAM) kunye namayeza okuthomalalisa uxinzelelo kunye.
Iziphumo ebezingalindelekanga eziqhelekileyo zokuthatha i-S-adenosyl-L-methionine (SAM) zinoku:
-intloko, isiyezi;
-ukuziva uxhalabile okanye uvalo;
- ukuhlanza, isisu esibuhlungu;
-urhudo, ukuqunjelwa;
-ukwanda kokubila; okanye.
-iingxaki zokulala (ukuphuthelwa).
Ndingayifumana i-S-Adenosyl-L-methionine (SAM) KuMthombo wokuTya?
Hayi.
I-S-Adenosyl-L-methionine (SAM) ayifumaneki ekutyeni. Iveliswa ngumzimba kwi-amino acid methionine kunye ne-ATP esebenza njengowona mthombo wamandla kwiiseli kuwo wonke umzimba.
Ingakanani idosi ye-S-Adenosyl-L-methionine(SAM) endinokulithatha?
Xa ucinga ngokusetyenziswa kwe-S-Adenosyl-L-methionine supplements, funa iingcebiso kugqirha wakho. Usenokucinga ngokubonana nogqirha oqeqeshelwe ukusebenzisa amayeza esintu/izongezelelo zempilo.
Ukuba ukhetha ukusebenzisa i-S-Adenosyl-L-methionine, sebenzisa njengoko uqondiswe kwiphakheji okanye njengoko uyalelwe ngugqirha wakho, usokhemisti, okanye omnye umboneleli wezempilo. Musa ukusebenzisa ngaphezulu kwale mveliso kunokuba kucetyiswa kwileyibhile.
Biza ugqirha wakho ukuba imeko oyinyangayo nge-S-Adenosyl-L-methionine ayiphucukanga, okanye ukuba iya iba mbi ngakumbi ngelixa usebenzisa le mveliso.
I-SAMe isoloko isetyenziswa ngabantu abadala kwiidosi ze-400-1600 mg ngomlomo yonke imihla ukuya kwiiveki ezili-12. Thetha nomboneleli wezempilo ukufumanisa ukuba yeyiphi idosi enokuba yeyona ilungileyo kwimeko ethile.
Kwenzeka ntoni ukuba ndiphoswe yi-S-Adenosyl-L-methionine Dosage
Tsiba idosi ephosiweyo ukuba kusondele ixesha ledosi yakho elandelayo ecwangcisiweyo. Musa ukusebenzisa i-SAMe eyongezelelweyo ukwenza idosi ephosiweyo.
Kwenzeka Ntoni Ukuba Ndigqithise Idosi?
Funa unyango olungxamisekileyo ukuba ugqithise umthamo.
Yintoni i-S-Adenosyl-L-methionine Drug Reaction?
Ukuba uphathwa kunye nawaphi na amayeza alandelayo, akufanele usebenzise i-S-Adenosyl-L-methionine ngaphandle kokuqala ukuthetha nomboneleli wakho wezempilo.
Ukuthatha i-S-Adenosyl-L-methionine ngexesha elinye njengoko la mayeza anokunyusa umngcipheko we-serotonin syndrome (imeko enokuba yingozi ebangelwa kukuba ne-serotonin eninzi emzimbeni wakho):
I-Dextromethorphan (i-Robitussin DM, ezinye iisyrups zokukhohlela)
I-Meperidine (iDemerol)
Pentazocine (Talwin)
Tramadol (Ultram)
Amayeza okudakumba
I-S-Adenosyl-L-methionine inokunxibelelana namayeza okudakumba, ukwandisa amandla okuba neziphumo ebezingalindelekanga ezibandakanya intloko ebuhlungu, isantya esingaqhelekanga okanye esikhawulezayo sentliziyo, ukuxhalaba, nokungaphumli, kwakunye nemeko enokuthi ibulaleke ebizwa ngokuba yiSerotonin Syndrome, ekhankanywe ngasentla. Ezinye iingcali zithi ukuthatha i-SAMe kwandisa amanqanaba e-serotonin ebuchosheni, kwaye ezininzi ii-antidepressants zenza okufanayo. Inkxalabo kukuba ukudibanisa ezimbini kunokunyusa i-serotonin kumanqanaba ayingozi. Thetha nogqirha wakho phambi kokuba usebenzise i-SAMe ukuba uthatha nawaphi na iyeza lokudakumba okanye ukuxhalaba.
I-Levodopa (L-dopa)
I-S-Adenosyl-L-methionine inokunciphisa ukusebenza kweli yeza kwi-Parkinson disease.
Amayeza esifo seswekile
I-S-Adenosyl-L-methionine inokunciphisa amanqanaba eswekile yegazi kwaye inokomeleza umphumo wamayeza esifo seswekile, okwandisa umngcipheko we-hypoglycemia (ishukela ephantsi yegazi).
Thenga i-S-Adenosyl-L-methionine (SAM) kunye ne-S-Adenosyl-L-methionine Disulfate Tosylate Powder kuMninzi
I-S-Adenosyl-L-methionine (ekwabizwa ngokuba yi-SAMe,SAM) luhlobo olwenziwe ngumntu lwekhemikhali eyenzeka ngokwemvelo emzimbeni. I-S-Adenosyl-L-methionine Disulfate Tosylate yifomathi ye-Disulfate Tosylate ye-S-Adenosyl-L-methionine.
I-S-Adenosyl-L-methionine isetyenziswe kunyango olulolunye njengoncedo olusebenzayo ekunciphiseni iimpawu zokudakumba, kunye nokunyanga i-osteoarthritis. Olunye usetyenziso olungangqinwanga ngophando luye lwabandakanya ukunyanga isifo sesibindi, isifo sentliziyo, i-schizophrenia, ukuxhalaba, i-tendonitis, iintlungu ezibuhlungu ezingapheliyo, intloko ebuhlungu ye-migraine, ukuxhuzula, i-premenstrual syndrome, kunye nesifo esingapheliyo sokukhathala.
I-S-Adenosyl-L-methionine Disulfate Tosylate ihlala ithengiswa njengezongezo zokutya kwimarike. I-Wisepowder njengomvelisi we-S-Adenosyl-L-methionine (SAM) powder kunye ne-S-Adenosyl-L-methionine Disulfate Tosylate Powder, inamandla okuvelisa kunye nokubonelela ngekhwalithi ephezulu ye-S-Adenosyl-L-methionine powder ye-S-Adenosyl-L -methionine (SAM) usetyenziso olongezelelweyo.
I-S-Adenosyl-L-methionine (SAM) powder kunye ne-S-Adenosyl-L-methionine Disulfate Tosylate powder Reference Reference
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- Anstee, QM; Usuku, CP (Novemba 2012). "S-Adenosylmethionine (SAMe) unyango kwisifo sesibindi: ukuphononongwa kobungqina bangoku kunye nokusetyenziswa kweklinikhi". Ijenali yeHepatology. 57 (5): 1097–109. doi:10.1016/j.jhep.2012.04.041. PMID 22659519.
- Födinger M, Hörl W, Sunder-Plassmann G (Jan–Feb 2000). "Ibhayoloji ye-molekyuli ye-5,10-methylenetetrahydrofolate reductase". J Nephroli. 13 (1): 20–33. PMID 10720211.
- McKie, Robin (10 April 2022). "Iingcali zebhayoloji zilumkisa ngesongezo 'sezempilo' se-SAMe esinetyhefu". UMjongi.
