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  3. I-Nootropics powder
  4. I-N-Acetyl-L-cysteine ​​ethyl ester (59587-09-6)

I-N-Acetyl-L-cysteine ​​ethyl ester (59587-09-6)

01 isishwankathelo

I-N-Acetyl-L-cysteine ​​ethyl ester powder 59587-09-6, zizinto zendalo okanye zokwenza izinto ezinokuphucula ukusebenza kwengqondo, ukuphucula ukusebenza kwengqondo kubantu abaphilayo. Ngokwesiqhelo yaziwa ngokuba ziNootropics kunye neziyobisi smart, ziye zafumana ukuthandwa kuluntu lwanamhlanje olunokhuphiswano kwaye zihlala zisetyenziswa ukukhulisa inkumbulo, ukugxila, ubuchule bokuyila, ubukrelekrele kunye nenkuthazo.


IStatus: Imveliso enkulu

02 (59587-09-6) ividiyo

03 (59587- 09-6) Ulwazi oluSisiseko

igama I-N-Acetyl-L-cysteine ​​ethyl ester
CAS 59587-09-6
Ukungcola 98%
Igama leKhemikhali I-N-Acetyl-L-cysteine ​​ethyl ester
I-NACET (R) -ethyl 2-acetamido-3-mercaptopropanoate
Iintetho ezifanayo N-Acetylcysteine ​​ethylester; (R) -Methyl 2-acetaMido-3-Mercaptopropanoate -Ethyl 2-acetamido-3-mercaptopropanoate; Ethyl (2R) -2-Acetamido-3-Sulfanyl-Propanoate; (2R)--Acetamido-2-Mercaptopropanoic Acid Ethyl Ester; (3R)--Acetamido-2-Mercapto-Propionic Acid Ethyl Ester
I-Molecular Formula C7H13NO3S
Isisindo somzimba 191.25 g / mol
Indawo yokunyibilika 197.0 ku-202.0 ° C
InChI Key I-MSMRAGNKRYVTCX-LURJTMIESA-N
imo solid
Kubonakala I powder emhlophe
Ubomi obulicla N / A
Umzimba N / A
yoGcino Imeko Gcina kwindawo epholileyo; Gcina isitya sivalekile kwindawo eyomileyo nenomoya owaneleyo
isicelo I-N-Acetyl-L-cysteine ​​ethyl ester powder isetyenziselwa ukukhulisa inkumbulo, ukugxila, ubuchule bokuyila, ubukrelekrele kunye nenkuthazo.
UXwebhu loVavanyo iyafumaneka

04 (59587-09-6) Inkcazo ngokubanzi

I-N-Acetyl-L-cysteine ​​ethyl ester powder (NACET): i-cyophine ye-cysteine ​​yesenoveli evunyelweyo kunye neempawu ezithile ezingaqhelekanga ze-pharmacokinetic kunye namandla anokubakho e-antioxidant.

05 I-N-Acetyl-L-cysteine ​​ethyl ester Imbali

06 (59587-09-6) Esebenzayo

07 Isicelo se-N-Acetyl-L-cysteine ​​ethyl ester

08 I-N-Acetyl-L-cysteine ​​ethyl ester Uphando ngakumbi

Uvavanyo lwakliniki olukhulu lwamva nje aluphumelelanga ukuqinisekisa iziphumo ezinokubakho ze-N-acetylcysteine ​​(NAC) ekuthinteleni izifo ezinxulumene noxinzelelo lwe-oxidative. Oku kungabangelwa kukuphazamiseka okuncinci kwe-bioavailability. Sasicinga ukuba i-esterization yeqela le-carboxyl le-NAC ukuvelisa i-N-acetylcysteine ​​ethyl ester (NACET) iya kuyonyusa kakhulu i-lipophilicity ye-NAC, ize ke iphucule kakhulu ikhemisi yayo. Kumsebenzi wangoku, sinika ingxelo ngepropathi ezimeleyo zamakhemikhali, ezezamayeza nezokulwa ii-anti-oxidant ze-NACET, ngakumbi ngokuthelekisa ngokuthe ngqo kunye ne-Ngengen yayo ye -gengener. Sifumanise ukuba i-NACET ingena ngokukhawuleza kwiigundane emva kolawulo lomlomo kodwa ifikelela kakhulu kwi-plasma. Oku kungenxa yempawu ezizodwa zeNACET: ingena ngokukhawuleza kwiiseli ekubanjiselwe ukuba iguqulwe ibe yi-NAC kunye ne-cysteine. Emva konyango ngomlomo, i-NACET (kodwa ingeyiyo i-NAC) yakwazi ukwandisa kakhulu umxholo we-glutathione uninzi lwezicubu ezivavanyiweyo, ubuchopho babandakanywa, kunye nokukhusela kwi-paracetamol inxication kwi-rat. I-NACET ikwanayo into ekhethekileyo yokuqokelelana kwii-erythrocyte zabantu apho isebenza njengomkhuseli onamandla nxamnye nomonakalo we-hydroperoxide-induction oxidative. Isifundo sethu sibonisa ukuba ukukwazi ukungena kwiiseli kunye nokuvelisa i-NAC kunye ne-cysteine, i-NACET inyuka ngokujikeleza kwe-hydrogen sulfide (H (2) S), yiyo loo nto imele umgqatswa olungileyo wokusetyenziswa komlomo njengomvelisi weH (2) S, kunye nezibonelelo ezicacileyo. ngaphezulu kwe-NAC. I-NACET inokubakho endaweni ye-NAC njenge-arhente ye-mucolytic, njenge-paracetamol antidote kunye njenge-antioxidant enxulumene ne-GSH.

09 Ukukhuphela uxwebhu ngo-N-Acetyl-L-cysteine ​​ethyl ester

IAAA

10 Isalathiso se-N-Acetyl-L-cysteine ​​ethyl ester Reference

  • I-S-Nitroso-N-acetyl-L-cysteine ​​ethyl ester (SNACET) kunye ne-N-acetyl-L-cysteine ​​ethyl ester (NACET) -I-Cysteine ​​esekwe kumachiza amachiza aphethe iiprofayili zekhemikhali ezingaqhelekanga zokusetyenziswa komlomo njenge-NO, H2S kunye nabaxhasi be-GSH kunye njengee-antioxidants: Iziphumo kunye nokujonga ngokubanzi. I-2018 Feb; 8 (1): 1-9. doi: 10.1016 / j.jpha.2017.12.003. Epub 2017 ngo-December 13. Uphengululo. I-PMID: 29568662
  • I-N-acetylcysteine ​​ethyl ester njenge-GSH yokuphucula iiseli eziphambili ze-endothelial zeseli: Isifundo sokuthelekisa kunye namanye amachiza. I-Oct ka-2018; 126: 202 209. doi: 10.1016 / j.freeradbiomed.2018.08.013. Epub 2018 Aug 14. PMID: 30114478
  • Esona sikhokelo siphezulu se-Nootropic: Yonke into ekufuneka uyazi [amava emi-5]

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