Umgubo weNmn (1094-61-7)

I-Nicotinamide mononucleotide powder ividiyo

Nmn powder Base Ulwazi

Nmn powder Inkcazo ngokubanzi

i-beta-Nicotinamide i-mononucleotide powder (1094-61-7) iyimveliso ye-extracellular Nicotinamide phosphoribosyltransferase (eNAMPT) yokusabela kunye nesitshixo esiphambili seNAD +. Kukunyamezelela i-glucose ukunganyamezeli ngokubuyisela amanqanaba e-NAD + kwiimpazamo ze-T2D ezine-TXNUMXD.

Ukonyusa ukuziva kwe-hepatic insulin kunye nokubuyisela ukubonakaliswa kohlobo olunxulumene noxinzelelo lwe-oxidative, impendulo yokuvuvukala, kunye nesigqi se-circadian, ngokuyinxalenye ngokusebenza kwe-SIRT1.

I-Nmn powder (1094-61-7) Imbali

I-Beta-Nicotinamide mononucleotide (NMN) ipowder iphakathi kwe-NAD + biosynthesis eveliswe kwi-nicotinamide nge-nicotinamide phosphoribosyltransferase (NAMPT) ekwabizwa ngokuba yi-NMN okanye i-nicotinamide ribotide. Kwizifundo zamva nje zezicelo ze-NMN kuthintelo kunye nokuchongwa kwezifo ezixhomekeke kubudala ezinje ngesifo seswekile, isifo se-neurodegenerative, isifo sentliziyo njlnjl., Iye yaba yenye yezona zinto zishushu kakhulu kwingxoxo yokulwa ukuguga, mva nje.

I-Nmn powder Mechanism of Action

I-beta-Nicotinamide mononucleotide (β-NMN) sisandulela se-biosynthetic ye-nicotinamide adenine dinucleotide (NAD +) eyaziwayo ukukhuthaza imveliso yeselula ye-NAD + kunye nokuchasene nezifo ezinxulumene nobudala ezinxulumene nokuhla kwamanqanaba eNAD +.

Nmn powder (1094-61-7) Isicelo

Iiseli eziguga. Ewe kunjalo, umsebenzi odlulileyo kwilebhu ye-Imai ubonakalisile ukuba ukunika i-beta-Nicotinamide mononucleotide kwiimpuku ezindala kunefuthe elihle kwimetabolism emzimbeni wonke, kubandakanya neziphumo ezihle kwimisipha yamathambo, ukusebenza kwesibindi, ukuxinana kwethambo, ukusebenza kwamehlo, uvakalelo lwe-insulin, ukusebenza komzimba ubunzima, kunye nenqanaba lomsebenzi.

Nmn powder (1094-61-7) Olunye uphando

Iiseli eziguga. Ewe kunjalo, umsebenzi odlulileyo kwilebhu ye-Imai ubonakalisile ukuba ukunika i-beta-Nicotinamide mononucleotide kwiimpuku ezindala kunefuthe elihle kwimetabolism emzimbeni wonke, kubandakanya neziphumo ezihle kwimisipha yamathambo, ukusebenza kwesibindi, ukuxinana kwethambo, ukusebenza kwamehlo, uvakalelo lwe-insulin, ukusebenza komzimba ubunzima, kunye nenqanaba lomsebenzi.

Umgubo weNmn (1094-61-7) Reference

• 1, iBogan, KL; IBrenner, C (2008). "I-Nicotinic acid, i-nicotinamide, kunye ne-nicotinamide riboside: uvavanyo lweemolekyuli ze-NAD + zandulela iivithamini kwisondlo sabantu". Uphengululo lonyaka lweZondlo. 28: 115-30. ikhonkco: 10.1146 / annurev.nutr.28.061807.155443. IINKCUKACHA:
• 2, IBrazil, JM; Li, C; Zhu, Y; IZhai, RG (kaJuni 2017). “I-NMNAT: Sisenzo esiyi-NAD +… Sisisithethi… Yi-neuroprotector”. Uluvo lwangoku kwiGenetics noPhuhliso. 44: 156-162. ikhonkco: 10.1016 / j.gde.2017.03.014. I-PMID 5515290.
• I-3, "uLawulo lwexesha elide lweNicotinamide Mononucleotide Mitigates Ukwehla okunxulumene nePhysiological Age kwiimpuku". Iseli Metabolism. 13 ngoDisemba 2016.
• 4, Stipp, David (Matshi 11, 2015). "Ngaphandle kweResveratrol: Inkqubo yokuChasana nokuguga yeNAD". Inethiwekhi yeNzululwazi yaseMelika.
• Yonke into ekufuneka uyazi ngeNicotinamide Riboside Chloride
• I-Nicotinamide Mononucleotide (NMN): Izibonelelo, iidosi, isongezelelo, uphando